NHS approves teplizumab, first drug shown to delay onset of type 1 diabetes by up to three years
NICE has approved teplizumab (brand name Tzield, made by Sanofi) for use on the NHS in England and Wales, making it the first drug capable of delaying the onset of type 1 diabetes. The immunotherapy drug, administered as a daily intravenous drip for two weeks, is approved for children aged eight and above and adults who are in a pre-symptomatic early stage of the condition. Clinical evidence suggests it can delay the appearance of symptoms by approximately 32 months, or roughly three years. NICE estimates around 1,100 people may be eligible in the first year, falling to approximately 820 in subsequent years. Type 1 diabetes affects around 400,000 people in the UK and requires lifelong insulin management. Patient groups and medical charities have welcomed the decision.
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